دکتر سید مهدی خوش فطرت- دانشگاه آیت الله بروجردی

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دکتر سید مهدی خوش فطرت

رئیس آزمایشگاه‌‌ها

استادیار

شیمی

پژوهش و فناوری

معرفی

تحصیلات

کارشناسی: شیمی محض

کارشناسی ارشد: شیمی تجزیه

دکتری: شیمی تجزیه

راه های ارتباطی

رایانامه

sm.khoshfetrat@abru.ac.ir

شماره تماس

شبکه‌های اجتماعی

مکان

ساختمان: علوم پایه

شرح وظایف

شيمي عمومي 2

شيمي تجزيه 2

آزمایشگاه شیمی تجزیه 1

آزمایشگاه شیمی تجزیه 2

آزمایشگاه شیمی عمومی 1

آزمایشگاه شیمی عمومی 2

آزمایشگاه شیمی تجزیه 3

روش های جداسازی

نانوشیمی

Label-free Multicolor Colorimetric and Fluorescence Dual Mode biosensing of HIV-1 DNA based on the Bifunctional NiFe2O4@UiO-66 Nanozyme, Iran National Science Foundation (INSF), 2022, Project cost: 220.000.000 IRR (In progress). Principle Investigator (PI).

Recycling the used water in boilers, softeners and condensers and reuse of recycled water in the production line in order to use water efficiently and reduce production costs and reduce depreciation of equipment. Jafarian Sugar Factory, 2021, Project cost: 1.300.000.000 IRR (Finished), Co-Investigator

Presenting effective and practical approach to preserve anion exchange resins in sugar cube line by the method of vacuum cooking in order to increase their endurance and efficiency, having the objective to decrease the production costs. Jafarian Sugar Factory, 2020, Project cost: 430.000.000 IRR. (Finished), Co-Investigator

Sensitive detection of aflatoxins in milk using aptarmers and nanoparticles by electrochemical methods. Baqiyatallah University of Medical Sciences, Tehran, Iran, 2015-2017, Project cost: 105.000.000 IRR. (Finished), Co-Investigator

Design and manufacture of PSA diagnostic kit. National Institute for Medical Research Development (NIMAD), 2019-2020, Project cost: 300.000.000 IRR. (Finished), Co-Investigator

Wireless electrochemiluminescence for simultaneous detection of RASSF1A and SLC5A8 tumor suppressor gene methylation in plasma or whole blood based on graphite-like carbon nitride nanosheets and metal-organic framework nanoparticles, Biosensor Research Center, Endocrinology and Metabolism Molecular–Cellular Sciences Institute, Tehran University of Medical Sciences, 2018-2020, Project cost: 200.000.000 IRR. (Finished), Principle Investigator (PI)

Electrochemiluminescence System Based on Graphitic Carbon Nitride Nanosheet @ Metal-Organic Framework for Detection of RASSF1A Tumor Suppressor Gene Methylation in Plasma of Suspected Persons, Iran National Science Foundation (INSF), 2019-2022, Project cost: 200.000.000 IRR. (Finished), Co-Investigator

نانوبیوالکتروشیمی

Translation of the book Analysis of Polymers-by Barbara-University of Isfahan Press. Year of publication: 2014.

تجزیه و تحلیل تصاویر میکروسکوپی SEM و TEM به کمک مجموعه نرم افزاری آنیکس (Anix)-انتشارات دانشگاه آیت ا... بروجردی (ره)- سال 1402

نشریات داخلی

Synthesis and cytotoxicity assessment of gold-coated magnetic iron oxide nanoparticles. Keshtkar, M., Shahbazi-Gahrouei, D., Mehrgardi, M., Aghaei, M., Seyyed Mehdi Khoshfetrat, 2018. Journal of biomedical physics & engineering 8(4), 357.

Aptamer-conjugated magnetic nanoparticles as targeted magnetic resonance imaging contrast agent for breast cancer. Journal of medical signals and sensors. Keshtkar, M., Shahbazi-Gahrouei, D., Seyyed Mehdi Khoshfetrat, Mehrgardi, M.A., Aghaei, M., 2016. 6(4), 243.

نشریات بین المللی

Enhanced electrochemiluminescence biosensing of gene-specific methylation in thyroid cancer patients' plasma based integrated Graphitic Carbon Nitride-encapsulated metal-organic framework nanozyme optimized by central composite design, Seyyed Mehdi Khoshfetrat, Parisa Seyed Dorraji, Lida Fotouhi, Mehdi Hosseini, Fatemeh Khatami, Hamid RezaMoazami, Kobra Omidfar, 2022, Sensors and Actuators B: Chemical, 131895, IF: 7.460

Smartphone-Based Electrochemiluminescence for Visual Simultaneous Detection of RASSF1A and SLC5A8 Tumor Suppressor Gene Methylation in Thyroid Cancer Patient Plasma, Seyyed Mehdi Khoshfetrat, Parisa Seyed Dorraji, Mohsen Shayan, Fatemeh Khatami, and Kobra Omidfar, 2022, Anal. Chem. 94, 22, 8005, IF: 6.986

Electrodeposited nickel nanocone/NiMoO4 nanocomposite designed as superior electrode materials for high performance supercapacitor, Sanaz Normohammadi ,Farzaneh Bahmani, Lida Fotouhi, Seyyed Mehdi Khoshfetrat, 2022, International Journal of Hydrogen Energy, 5220, IF:5.816

Electrochemical immunosensor for determination of cardiac troponin I using two-dimensional metal-organic framework/Fe3O4–COOH nanosheet composites loaded with thionine and pCTAB/DES modified electrode, Anita Ahmadi, Seyyed Mehdi Khoshfetrat, Zahra Mirzaeizadeh, Shima Kabiri, Javad Rezaie, Kobra Omidfar, 2022, Talanta, 122911, IF: 6.057

Cascade Electrochemiluminescence-based integrated Graphitic Carbon Nitride-encapsulated metal-organic framework nanozyme for prostate-specific antigen biosensing. Seyyed Mehdi Khoshfetrat, Pegah Hashemi, Abbas Afkhami, Ali Hajian, Hasan Bagheri. 2021, Sensors and Actuators B: Chemical, 130658, IF: 7:40

Fabrication and design of new redox active azure A/ 3D graphene aerogel and conductive trypan blue– nickel MOF nanosheet array electrodes for an asymmetric supercapattery. Tahereh Sadeghian Renani, Seyyed Mehdi Khoshfetrat, Jalal Arjomandi, Hu Shi and Sadegh Khazalpour. 2021. Journal of Materials Chemistry A, 12853. IF: 12.732.

Electrochemiluminescence paper-based screen-printed electrode for HbA1c detection using two-dimensional zirconium metal-organic framework/Fe3O4 nanosheet composites decorated with Au nanoclusters, Anita Ahmadi, Seyyed Mehdi Khoshfetrat, Shima Kabiri, Parisa Seyed Dorraji, Bagher Larijani, 2021, Kobra Omidfar, Microchimica Acta, 1-11, IF: 5.833

Impedimetric Paper-Based Enzymatic Biosensor using Electrospun Cellulose Acetate Nanofiber and Reduced Graphene Oxide for Detection of Glucose from Whole Blood. Ahmadi, A., Seyyed Mehdi Khoshfetrat, Kabiri, S., Fotouhid, L., Dorrajid, P.S., Omidfar, K., 2021. IEEE Sens. J., 1-1. IF: 3.076

Electrochemiluminescent biosensor for ultrasensitive detection of lymphoma at the early stage using CD20 markers as B cell-specific antigens. Fazlali, F., Hashemi, P., Seyyed Mehdi Khoshfetrat, Halabian, R., Baradaran, B., Johari-Ahar, M., Karami, P., Hajian, A., Bagheri, H., 2020. Bioelectrochemistry, 107730. IF: 4.722.

Point-of-care biosensors in medicine: a brief overview of our achievements in this field based on the conducted research in EMRI (endocrinology and metabolism research Institute of Tehran University of medical sciences) over the past fourteen years. Kobra Omidfar, Anita Ahmadi, Leila Syedmoradi, Seyyed Mehdi Khoshfetrat, Bagher Larijani, 2020, Journal of Diabetes & Metabolic Disorders, 1-5.

Enhanced Visual Wireless Electrochemiluminescence Immunosensing of Prostate-Specific Antigen Based on the Luminol Loaded into MIL-53(Fe)-NH2 Accelerator and Hydrogen Evolution Reaction Mediation. Seyyed Mehdi Khoshfetrat, Khoshsafar, H., Afkhami, A., Mehrgardi, M.A., Bagheri, H., 2019. Anal. Chem. 91(9), 6383-6390. IF: 6.785

Voltammetric immunosensor for E-cadherin promoter DNA methylation using a Fe3O4-citric acid nanocomposite and a screen-printed carbon electrode modified with poly (vinyl alcohol) and reduced graphene oxide. Khodaei, R., Ahmady, A., Seyyed Mehdi Khoshfetrat, Kashanian, S., Tavangar, S.M., Omidfar, K., 2019. Microchimica Acta 186(3), 1-12. IF: 6.232

Electrochemical sensors and biosensors based on the use of polyaniline and its nanocomposites: A review on recent advances. Shoaie, N., Daneshpour, M., Azimzadeh, M., Mahshid, S., Seyyed Mehdi Khoshfetrat, Jahanpeyma, F., Gholaminejad, A., Omidfar, K., Foruzandeh, M., 2019. Microchimica Acta 186(7), 1-29. IF: 6.232.

Rich-color visual genotyping of single-nucleotide polymorphisms based on platinum nanoparticle–induced etching of gold nanorods. Bishkul, H., Seyyed Mehdi Khoshfetrat, Noori, A., Mehrgardi, M.A., Mousavi, M.F., 2019. Emergent Materials 2(3), 351-361.

Visual electrochemiluminescence biosensing of aflatoxin M1 based on luminol-functionalized, silver nanoparticle-decorated graphene oxide. Seyyed Mehdi Khoshfetrat, Bagheri, H., Mehrgardi, M.A., 2018. Biosens. Bioelectron. 100(Supplement C), 382-388. IF: 10.257.

Amplified detection of leukemia cancer cells using an aptamer-conjugated gold-coated magnetic nanoparticles on a nitrogen-doped graphene modified electrode. Seyyed Mehdi Khoshfetrat, Mehrgardi, M.A., 2017. Bioelectrochemistry 114, 24-32. IF: 4.722.

Prostate Specific Antigen Immunosensor Based on Biotinylated-Antibody/Cyclodextrin Inclusion Complex: Fabrication and Electrochemical Studies, Mir F. Mousavi, Masoud Amiri, Abolhassan Noori, Seyyed Mehdi Khoshfetrat, 2017, Electroanalysis 29, 2818-2831. IF: 3.223

Wireless Electrochemiluminescence Bipolar Electrode Array for Visualized Genotyping of Single Nucleotide Polymorphism. Seyyed Mehdi Khoshfetrat, Ranjbari, M., Shayan, M., Mehrgardi, M.A., Kiani, A., 2015. Anal. Chem. 87(16), 8123-8131. IF: 6.785.

Electrochemical Genotyping of Single‐Nucleotide Polymorphisms by using Monobase‐Conjugated Modified Nanoparticles. Seyyed Mehdi Khoshfetrat, Mehrgardi, M.A., 2014b. ChemElectroChem 1(4), 779-786. IF: 4.154.

Amplified electrochemical genotyping of single-nucleotide polymorphisms using a graphene–gold nanoparticles modified glassy carbon platform. Seyyed Mehdi Khoshfetrat, Mehrgardi, M.A., 2015. RSC Advances 5(37), 29285-29293. IF: 3.119.

Dual amplification of single nucleotide polymorphism detection using graphene oxide and nanoporous gold electrode platform. Seyyed Mehdi Khoshfetrat, Mehrgardi, M.A., 2014a. Analyst 139(20), 5192-5199. IF: 3.978.

Carbon nanotube composite coated platinum electrode for detection of Ga (III). Abbaspour, A., Seyyed Mehdi Khoshfetrat, Sharghi, H., Khalifeh, R., 2011. J. Hazard. Mater. 185(1), 101-106. IF: 9.038.

همایش های داخلی

Visual Smartphone-Based detection using the Integration of Bipolar electrochemistry and Electrochemiluminescence, 21th Interntionl Chemitsry Congress (ICS), Azarbaijan Shahid Madani University, Iran, Oral Presentation.

Smartphone-based electrochemiluminescence for visual simultaneous detection of RASSF1A and SLC5A8 tumor suppressor gene methylation in thyroid cancer patients plasma, 2022, 1st National Conference on Applied Researches in Basic Sciences (Mathematics, Chemistry, and Physics) (ARBS2022), University of Ayatollah Boroujerdi, Iran, Poster.

Label-free Multicolor Colorimetric and Fluorescence Dual Mode biosensing of HIV-1 DNA based on the Bifunctional NiFe2O4@UiO-66 Nanozyme, 2022, 1st National Conference on Applied Researches in Basic Sciences (Mathematics, Chemistry, and Physics) (ARBS2022), University of Ayatollah Boroujerdi, Iran, Oral Presentation.

Electrochemiluminescence-based Nanozyme for Prostate-Specific Antigen using the Luminol-loaded Graphitic Carbon Nitride Nanosheets (C3N4 NS)-encapsulated NH2-MIL(53)-Fe, August 2021, Kharazmi University, 14th Biennial Electrochemistry Seminar of IRAN, Poster

Preparation of vanadium-copper nanocomposite as a nanocatalyst anchored on carbon nanofibers to modification of cathode and improvement in rechargeable Li- CO2 batteries performance, August 2021, Kharazmi University, 14th Biennial Electrochemistry Seminar of IRAN, Poster

Fabrication and Design of New Redox Active Azure A/3D Graphene Aerogel Electrodes for Supercapacitor, August 2021, Kharazmi University, 14th Biennial Electrochemistry Seminar of IRAN, Poster

Fabrication and Design of New Conductive Trypan Blue–Nickel MOF Nanosheet Array Electrodes for rechargeable battery, August 2021, Kharazmi University, 14th Biennial Electrochemistry Seminar of IRAN, Poster

Synthesis of Conductive Trypan Blue–Nickel MOF Nanosheet Array for an Asymmetric Supercapattery, 4th national Congress of Chemistry and Nanochemistry from Research to Technology, Sept. 2021, Poster.

Comprehensive program of the National Congress on Cancer Nov. 2009, Center for International Symposium on Iran’s Broadcasting, Tehran, Iran. , Poster

Electrocatalytic oxidation of dihydronicotinamide adenine dinucleotide on nickel hexacyanoferrate nanoparticles-modified carbon past electrode Sept. 2014, 7th Seminar on Analytical Chemistery, Kashan, Iran , Poster

Electrochemical detection of single nucleotide polymorphisms using monobase-modified silver nanoparticle July 2010, 10th Iranian bicultural electrochemical conference, Tehran, Iran , Poster

Detection of Single Nucleotide Polymorphisms using Graphene Oxide -base Nanoporous Gold Electrode Platform Feb. 2010, 20th International Conference on Chemical Analysis, Isfahan, Iran. , Poster

Visualized Genotyping of Single Nucleotide Polymorphism by Integrating of Bipolar Electrochemistry and Electrochemiluminescence Feb. 2011, 21st Iranian Chemical Analysis Conference, Ahvaz, Iran. Oral

همایش های بین المللی

Preparation of Nanomaterial-based Artificial Enzymes using Integrated Graphitic Carbon Nitride Nanosheet-encapsulated Metal-Organic Framework Optimized by Central Composite Design for Enhanced Electrochemiluminescence Biosensing of Gene-Specific Methylation Seyyed Mehdi Khoshfetrat, F. Moradnia, S. Jalalifar, 2021, 6th International Conference on Frontiers of Composite Materials, Melbourne, Australia (Oral Presentation).

Preparation of Graphitic Carbon Nitride Nanosheet-Encapsulated Nano Metal-Organic Framework Nanozyme for ElectrochemiluminescencProstate-Specific Antigen Biosensing, Seyyed Mehdi Khoshfetrat, F. Moradnia, M. Soleymani, M. Hosseini. 2021, 3rd International Conference on Engineering Materials, Chengdu, China (Oral Presentation).

Executive Secretary in 1st National Conference on Applied Researches in Basic Sciences (Mathematics, Chemistry, and Physics) (ARBS2022) held by University of Ayatollah Boroujerdi, Iran, May 26-27, 2022.

Technical Adviser in AZSENSE

Master Instructor of "Electrochemical Impedance In Biosensor and Supercapacitor" course for1st National Conference on Applied Researches in Basic Sciences (Mathematics, Chemistry, and Physics)(ARBS2022), University of Ayatollah Boroujerdi, Iran, May 26-27, 2022

Workshop Solubilization, University of Ayatollah Boroujerdi, Iran, August 26, 2021

Membership in the Iranian Chemical Society 2. Membership in China Chemical Societ

Distinguished researcher in Ayatollah Boroujerdi university. 2022

Distinguished researcher in Elite Foundation in Shahid Ashtiani's project.

Distinguished researcher in Boroujerd province, 2022.

Iranian national science foundation research fellowship, 2019.

Nominee student nomination in Isfahan province.

First rank graduated student in M.Sc. at Isfahan university

Nano Headquarter’s Third Nominee Commercialization Plan

Invention of the blocking and washing buffers entitled ‘Ready to use blocking and washing buffers for application in biochemical tests’ Apr. 2019. Patent No. 98271